An (89)Zr-HDL PET Tracer Monitors Response to a CSF1R Inhibitor

The immune function within the tumor microenvironment has become a prominent therapeutic target, with tumor-associated macrophages (TAMs) playing a critical role in immune suppression. We propose an (89)Zr-labeled high-density lipoprotein ((89)Zr-HDL) nanotracer as a means of monitoring response to...

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Detalhes bibliográficos
Publicado no:J Nucl Med
Main Authors: Mason, Christian A., Kossatz, Susanne, Carter, Lukas M., Pirovano, Giacomo, Brand, Christian, Guru, Navjot, Pérez-Medina, Carlos, Lewis, Jason S., Mulder, Willem J.M., Reiner, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Nuclear Medicine 2020
Assuntos:
Immunotherapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067531/
https://ncbi.nlm.nih.gov/pubmed/31420495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.119.230466
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