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Effect of bezafibrate on hepatic oxidative stress: comparison between conventional experimental doses and clinically-relevant doses in mice

Several rodent studies have demonstrated that fibrate drugs can activate peroxisome proliferator-activated receptor α (PPARα) and increase reactive oxygen species (ROS) production. The persistence of strong PPARα activation is considered to be a possible mechanism related to the adverse effects of t...

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Dettagli Bibliografici
Pubblicato in:Redox Rep
Autori principali: Nakajima, Takero, Tanaka, Naoki, Li, Gang, Hu, Rui, Kamijo, Yuji, Hara, Atsushi, Aoyama, Toshifumi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067332/
https://ncbi.nlm.nih.gov/pubmed/20594415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1179/174329210X12650506623807
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