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Demethylation of theophylline (1,3-dimethylxanthine) to 1-methylxanthine: the first step of an antioxidising cascade

The reaction of theophylline with HO(•) radical, produced by photolytic methods at pH 7, was studied in aqueous solution and the products characterised by HPLC and GC-MS. In addition to the expected 1,3-dimethyluric acid, the formation of 1-methylxanthine and, to a lesser extent, of 3-methylxanthine...

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Vydáno v:Redox Rep
Hlavní autoři: Santos, Pedro M.P., Silva, Saúl A.G., Justino, Gonçalo C., Vieira, Abel J.S.C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067326/
https://ncbi.nlm.nih.gov/pubmed/20594417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1179/174329210X12650506623726
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