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Downregulation of miR-33 Has Protective Effect Against Aβ(25–35)-Induced Injury in SH-SH-SY5Y Cells

BACKGROUND: Alzheimer disease (AD) is a significant health issue for the elderly, and there are at present no clinically effective anti-AD agents. Prevention of Aβ-induced neurotoxicity is proposed as a possible modality for treatment of AD. miR-33 has been proven to promote Aβ secretion and impair...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Med Sci Monit
Main Authors: Wang, Xiaoping, Li, Xiaojia, Huang, Bin, Yang, Lili, Chen, Kai, Zhao, Dongdong, Luo, Xiangdong, Wang, Yingji
Format: Artigo
Jezik:Inglês
Izdano: International Scientific Literature, Inc. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067051/
https://ncbi.nlm.nih.gov/pubmed/32119650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.921026
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