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Highly-selective µ-opioid receptor antagonism does not block L-DOPA-induced dyskinesia in a rodent model
OBJECTIVES: Dopamine-replacement utilizing L-DOPA is still the mainstay treatment for Parkinson’s disease (PD), but often leads to development of L-DOPA-induced dyskinesia (LID), which can be as debilitating as the motor deficits. There is currently no satisfactory pharmacological adjunct therapy. T...
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| Udgivet i: | BMC Res Notes |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7066739/ https://ncbi.nlm.nih.gov/pubmed/32164786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-020-04994-7 |
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