Prognostic and Predictive Value of Microsatellite Instability, Inflammatory Reaction and PD‐L1 in Gastric Cancer Patients Treated with Either Adjuvant 5‐FU/LV or Sequential FOLFIRI Followed by Cisplatin and Docetaxel: A Translational Analysis from the ITACA‐S Trial

BACKGROUND: Patients with high microsatellite instability (MSI) gastric cancer (GC) show improved survival and no benefit or harm from adjuvant and/or perioperative chemotherapy. The role of immune microenvironment in GC is largely unknown. MATERIALS AND METHODS: In the present study, 256 tumor tiss...

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Bibliografski detalji
Izdano u:Oncologist
Glavni autori: Di Bartolomeo, Maria, Morano, Federica, Raimondi, Alessandra, Miceli, Rosalba, Corallo, Salvatore, Tamborini, Elena, Perrone, Federica, Antista, Maria, Niger, Monica, Pellegrinelli, Alessandro, Randon, Giovanni, Pagani, Filippo, Martinetti, Antonia, Fucà, Giovanni, Pietrantonio, Filippo
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Inc. 2019
Teme:
Gastrointestinal Cancer
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066701/
https://ncbi.nlm.nih.gov/pubmed/32162808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2019-0471
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