Human Tissue Kallikrein 1 Improves Erectile Dysfunction of Streptozotocin-Induced Diabetic Rats by Inhibition of Excessive Oxidative Stress and Activation of the PI3K/AKT/eNOS Pathway

OBJECTIVE: To investigate the protective effects and mechanisms of human tissue kallikrein 1 (hKLK1) on type 1 diabetes mellitus- (DM-) induced erectile dysfunction in rats. Materials and Methods. The homozygous transgenic rats (TGR) harboring the hKLK1 gene and age-matched wild-type Sprague Dawley...

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Veröffentlicht in:Oxid Med Cell Longev
Hauptverfasser: Luan, Yang, Cui, Kai, Tang, Zhe, Ruan, Yajun, Liu, Kang, Wang, Tao, Chen, Zhong, Wang, Shaogang, Liu, Jihong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066404/
https://ncbi.nlm.nih.gov/pubmed/32190176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/6834236
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