High-Resolution Dissection of Chemical Reprogramming from Mouse Embryonic Fibroblasts into Fibrocartilaginous Cells

Articular cartilage injury and degeneration causing pain and loss of quality-of-life has become a serious problem for increasingly aged populations. Given the poor self-renewal of adult human chondrocytes, alternative functional cell sources are needed. Direct reprogramming by small molecules potent...

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Veröffentlicht in:Stem Cell Reports
Hauptverfasser: Chen, Yishan, Wu, Bingbing, Lin, Junxin, Yu, Dongsheng, Du, Xiaotian, Sheng, Zixuan, Yu, Yeke, An, Chengrui, Zhang, Xiaoan, Li, Qikai, Zhu, Shouan, Sun, Heng, Zhang, Xianzhu, Zhang, Shufang, Zhou, Jing, Bunpetch, Varitsara, El-Hashash, Ahmed, Ji, Junfeng, Ouyang, Hongwei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066361/
https://ncbi.nlm.nih.gov/pubmed/32084387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.01.013
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