An Extended Culture System that Supports Human Primordial Germ Cell-like Cell Survival and Initiation of DNA Methylation Erasure

The development of an in vitro system in which human primordial germ cell-like cells (hPGCLCs) are generated from human pluripotent stem cells (hPSCs) has been invaluable to further our understanding of human primordial germ cell (hPGC) specification. However, the means to evaluate the next fundamen...

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Pubblicato in:Stem Cell Reports
Autori principali: Gell, Joanna J., Liu, Wanlu, Sosa, Enrique, Chialastri, Alex, Hancock, Grace, Tao, Yu, Wamaitha, Sissy E., Bower, Grace, Dey, Siddharth S., Clark, Amander T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066331/
https://ncbi.nlm.nih.gov/pubmed/32059791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.01.009
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