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Therapy With Carboplatin and Anti-PD-1 Antibodies Before Surgery Demonstrates Sustainable Anti-Tumor Effects for Secondary Cancers in Mice With Triple-Negative Breast Cancer

Patients with triple-negative breast cancer (TNBC) suffer an unfavorable prognosis. Carboplatin (CBDCA) as a cytotoxic reagent has been widely administered to patients with cancer including TNBC. Programmed cell death protein 1 (PD-1) is an immune checkpoint, blockade of which unleashes T cell funct...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Gao, Meizhuo, Wang, Tie, Ji, Litong, Bai, Shuping, Tian, Lining, Song, Hongjiang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066228/
https://ncbi.nlm.nih.gov/pubmed/32194569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00366
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