Fibroblast Growth Factor 9 is expressed by activated hepatic stellate cells and promotes progression of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is closely associated with liver fibrosis. Hepatic stellate cells (HSC) and cancer-associated myofibroblasts are key players in liver fibrogenesis and hepatocarcinogenesis. Overexpression of fibroblast growth factor (FGF) receptors contributes to HCC development and pr...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Seitz, Tatjana, Freese, Kim, Dietrich, Peter, Thasler, Wolfgang Erwin, Bosserhoff, Anja, Hellerbrand, Claus
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066162/
https://ncbi.nlm.nih.gov/pubmed/32161315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61510-4
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