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Critical role for Slam/SAP signaling in the thymic developmental programming of IL-17- and IFN-γ-producing γδ T cells

During thymic development, mouse γδ T cells commit to either an IFN-γ- or an IL-17-producing phenotype through mechanisms that remain unclear. Here, we investigated the extent to which the SLAM/SAP signaling pathway regulates the functional programming of γδ T cells. Characterization of SLAM family...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Dienz, Oliver, DeVault, Victoria L., Musial, Shawn C., Mistri, Somen K., Mei, Linda, Baraev, Aleksandr, Dragon, Julie A., Krementsov, Dimitry, Veillette, Andre, Boyson, Jonathan E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065973/
https://ncbi.nlm.nih.gov/pubmed/32024701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901082
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