Direct measurement of vertical forces shows correlation between mechanical activity and proteolytic ability of invadopodia

Mechanobiology plays a prominent role in cancer invasion and metastasis. The ability of a cancer to degrade extracellular matrix (ECM) is likely connected to its invasiveness. Many cancer cells form invadopodia—micrometer-sized cellular protrusions that promote invasion through matrix degradation (p...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Adv
Egile Nagusiak: Dalaka, E., Kronenberg, N. M., Liehm, P., Segall, J. E., Prystowsky, M. B., Gather, M. C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Association for the Advancement of Science 2020
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065877/
https://ncbi.nlm.nih.gov/pubmed/32195338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax6912
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