Integrative analysis of the genomic and transcriptomic landscape of double-refractory multiple myeloma

In multiple myeloma, novel treatments with proteasome inhibitors (PIs) and immunomodulatory agents (IMiDs) have prolonged survival but the disease remains incurable. At relapse, next-generation sequencing has shown occasional mutations of drug targets but has failed to identify unifying features tha...

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Vydáno v:Blood Adv
Hlavní autoři: Ziccheddu, Bachisio, Biancon, Giulia, Bagnoli, Filippo, De Philippis, Chiara, Maura, Francesco, Rustad, Even H., Dugo, Matteo, Devecchi, Andrea, De Cecco, Loris, Sensi, Marialuisa, Terragna, Carolina, Martello, Marina, Bagratuni, Tina, Kastritis, Efstathios, Dimopoulos, Meletios A., Cavo, Michele, Carniti, Cristiana, Montefusco, Vittorio, Corradini, Paolo, Bolli, Niccolo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2020
Témata:
Lymphoid Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065476/
https://ncbi.nlm.nih.gov/pubmed/32126144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000779
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