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Adaptive multiarm multistage clinical trials

Two methods for designing adaptive multiarm multistage (MAMS) clinical trials, originating from conceptually different group sequential frameworks are presented, and their operating characteristics are compared. In both methods pairwise comparisons are made, stage‐by‐stage, between each treatment ar...

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Detalhes bibliográficos
Publicado no:Stat Med
Main Authors: Ghosh, Pranab, Liu, Lingyun, Mehta, Cyrus
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065228/
https://ncbi.nlm.nih.gov/pubmed/32048313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.8464
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