HSP70 Inhibition Leads to the Activation of Proteasomal System under Mild Hyperthermia Conditions in Young and Senescent Fibroblasts

Aging has been characterized with the accumulation of oxidized proteins, as a consequence of progressive decline in proteostasis capacity. Among others, proteasomal system is an efficient protein turnover complex to avoid aggregation of oxidized proteins. Heat shock protein 70 (HSP70) is another cri...

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Detaylı Bibliyografya
Yayımlandı:Oxid Med Cell Longev
Asıl Yazarlar: Bozaykut, Perinur, Sozen, Erdi, Kaga, Elif, Ece, Asli, Ozaltin, Esra, Bergquist, Jonas, Kartal Ozer, Nesrin, Karademir Yilmaz, Betul
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Hindawi 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064868/
https://ncbi.nlm.nih.gov/pubmed/32190179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/9369524
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