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The HIV-1 Accessory Protein Vpu Downregulates Peroxisome Biogenesis

Human immunodeficiency virus type 1 (HIV-1) establishes lifelong infections in humans, a process that relies on its ability to thwart innate and adaptive immune defenses of the host. Recently, we reported that HIV-1 infection results in a dramatic reduction of the cellular peroxisome pool. Peroxisom...

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Bibliographic Details
Published in:mBio
Main Authors: Xu, Zaikun, Lodge, Robert, Power, Christopher, Cohen, Eric A., Hobman, Tom C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064786/
https://ncbi.nlm.nih.gov/pubmed/32127461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.03395-19
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