The Pseudomonas aeruginosa Lectin LecB Causes Integrin Internalization and Inhibits Epithelial Wound Healing

The opportunistic bacterium Pseudomonas aeruginosa produces the fucose-specific lectin LecB, which has been identified as a virulence factor. LecB has a tetrameric structure with four opposing binding sites and has been shown to act as a cross-linker. Here, we demonstrate that LecB strongly binds to...

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Pubblicato in:mBio
Autori principali: Thuenauer, Roland, Landi, Alessia, Trefzer, Anne, Altmann, Silke, Wehrum, Sarah, Eierhoff, Thorsten, Diedrich, Britta, Dengjel, Jörn, Nyström, Alexander, Imberty, Anne, Römer, Winfried
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064779/
https://ncbi.nlm.nih.gov/pubmed/32156827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.03260-19
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