The Absence of (p)ppGpp Renders Initiation of Escherichia coli Chromosomal DNA Synthesis Independent of Growth Rates

The initiation of Escherichia coli chromosomal DNA replication starts with the oligomerization of the DnaA protein at repeat sequences within the origin (ori) region. The amount of ori DNA per cell directly correlates with the growth rate. During fast growth, the cell generation time is shorter than...

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Publicat a:mBio
Autors principals: Fernández-Coll, Llorenç, Maciag-Dorszynska, Monika, Tailor, Krishma, Vadia, Stephen, Levin, Petra Anne, Szalewska-Palasz, Agnieszka, Cashel, Michael
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064777/
https://ncbi.nlm.nih.gov/pubmed/32156825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.03223-19
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