Characteristics of Tumor-Infiltrating Lymphocytes Prior to and During Immune Checkpoint Inhibitor Therapy

The tumor immune contexture plays a major role for the clinical outcome of patients. High densities of CD45RO(+) T helper 1 cells and CD8(+) T cells are associated with improved survival of patients with various cancer entities. In contrast, a higher frequency of tumor-infiltrating M2 macrophages is...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Plesca, Ioana, Tunger, Antje, Müller, Luise, Wehner, Rebekka, Lai, Xixi, Grimm, Marc-Oliver, Rutella, Sergio, Bachmann, Michael, Schmitz, Marc
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064638/
https://ncbi.nlm.nih.gov/pubmed/32194568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00364
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