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Therapeutic mechanism of cord blood mononuclear cells via the IL-8-mediated angiogenic pathway in neonatal hypoxic-ischaemic brain injury

In a clinical trial of cerebral palsy, the level of plasma interleukin-8 (IL-8) was increased, correlated with motor improvement, after human umbilical cord blood mononuclear cell (hUCBC) infusion. This study aimed to elucidate the role of IL-8 in the therapeutic effects of hUCBCs in a mouse model o...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cho, Kye Hee, Choi, Jee In, Kim, Jin-Ock, Jung, Joo Eun, Kim, Dong-Wook, Kim, MinYoung
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064601/
https://ncbi.nlm.nih.gov/pubmed/32157146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61441-0
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