MicroRNA-mRNA networks define translatable molecular outcome phenotypes in osteosarcoma

There is a lack of well validated prognostic biomarkers in osteosarcoma, a rare, recalcitrant disease for which treatment standards have not changed in over 20 years. We performed microRNA sequencing in 74 frozen osteosarcoma biopsy samples, constituting the largest single center translationally ana...

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Pubblicato in:Sci Rep
Autori principali: Lietz, Christopher E., Garbutt, Cassandra, Barry, William T., Deshpande, Vikram, Chen, Yen-Lin, Lozano-Calderon, Santiago A., Wang, Yaoyu, Lawney, Brian, Ebb, David, Cote, Gregory M., Duan, Zhenfeng, Hornicek, Francis J., Choy, Edwin, Petur Nielsen, G., Haibe-Kains, Benjamin, Quackenbush, John, Spentzos, Dimitrios
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064533/
https://ncbi.nlm.nih.gov/pubmed/32157112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61236-3
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