Zerumbone Modulates α(2A)-Adrenergic, TRPV1, and NMDA NR2B Receptors Plasticity in CCI-Induced Neuropathic Pain In Vivo and LPS-Induced SH-SY5Y Neuroblastoma In Vitro Models

Zerumbone has shown great potential in various pathophysiological models of diseases, particularly in neuropathic pain conditions. Further understanding the mechanisms of action is important to develop zerumbone as a potential anti-nociceptive agent. Numerous receptors and pathways function to inhib...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Chia, Jasmine Siew Min, Izham, Noor Aishah Mohammed, Farouk, Ahmad Akira Omar, Sulaiman, Mohd Roslan, Mustafa, Sanam, Hutchinson, Mark R., Perimal, Enoch Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064019/
https://ncbi.nlm.nih.gov/pubmed/32194397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00092
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