Pravastatin for early‐onset pre‐eclampsia: a randomised, blinded, placebo‐controlled trial

OBJECTIVE: Women with pre‐eclampsia have elevated circulating levels of soluble fms‐like tyrosine kinase‐1 (sFlt‐1). Statins can reduce sFlt‐1 from cultured cells and improve pregnancy outcome in animals with a pre‐eclampsia‐like syndrome. We investigated the effect of pravastatin on plasma sFlt‐1 l...

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Detalles Bibliográficos
Publicado en:BJOG
Main Authors: Ahmed, A, Williams, DJ, Cheed, V, Middleton, LJ, Ahmad, S, Wang, K, Vince, AT, Hewett, P, Spencer, K, Khan, KS, Daniels, JP
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
Assuntos:
Maternal Medicine
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063986/
https://ncbi.nlm.nih.gov/pubmed/31715077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1471-0528.16013
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