Reconstruction and Validation of a Genome-Scale Metabolic Model of Streptococcus oralis (iCJ415), a Human Commensal and Opportunistic Pathogen

The mitis group of streptococci (MGS) is a member of the healthy human microbiome in the oral cavity and upper respiratory tract. Troublingly, some MGS are able to escape this niche and cause infective endocarditis, a severe and devastating disease. Genome-scale models have been shown to be valuable...

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Detalles Bibliográficos
Publicado en:Front Genet
Main Authors: Jensen, Christian S., Norsigian, Charles J., Fang, Xin, Nielsen, Xiaohui C., Christensen, Jens Jørgen, Palsson, Bernhard O., Monk, Jonathan M.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Genetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063969/
https://ncbi.nlm.nih.gov/pubmed/32194617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00116
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