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Hemispheric asymmetry in the human brain and in Parkinson’s disease is linked to divergent epigenetic patterns in neurons

BACKGROUND: Hemispheric asymmetry in neuronal processes is a fundamental feature of the human brain and drives symptom lateralization in Parkinson’s disease (PD), but its molecular determinants are unknown. Here, we identify divergent epigenetic patterns involved in hemispheric asymmetry by profilin...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Li, Peipei, Ensink, Elizabeth, Lang, Sean, Marshall, Lee, Schilthuis, Meghan, Lamp, Jared, Vega, Irving, Labrie, Viviane
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063821/
https://ncbi.nlm.nih.gov/pubmed/32151270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-01960-1
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