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SYSTEMIC UPTAKE, ALBUMIN AND HEMOGLOBIN BINDING OF [(14)C]2,3-BUTANEDIONE ADMINISTERED BY INTRATRACHEAL INSTILLATION IN MALE HARLAN SPRAGUE DAWLEY RATS AND OROPHARYNGEAL ASPIRATION IN MALE B6C3F1/N MICE

2,3-Butanedione (BD) is a reactive diketone in artificial butter flavors that is thought to cause bronchiolitis obliterans in workers in microwave popcorn manufacturing. Bronchiolitis obliterans is generally not diagnosed until irreversible damage has occurred; therefore a biomarker of early exposur...

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Podrobná bibliografie
Vydáno v:Chem Biol Interact
Hlavní autoři: Fennell, Timothy R., Morgan, Daniel L., Watson, L. Scott, Dhungana, Suraj, Waidyanatha, Suramya
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063503/
https://ncbi.nlm.nih.gov/pubmed/25559854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2014.12.029
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