Berberine Inhibits Nod-Like Receptor Family Pyrin Domain Containing 3 Inflammasome Activation and Pyroptosis in Nonalcoholic Steatohepatitis via the ROS/TXNIP Axis

Berberine (BBR), an isoquinoline alkaloid originating from herbal plants, has been deemed beneficial for non-alcoholic fatty liver disease. Increasing evidence has demonstrated that Nod-like receptor family pyrin domain containing 3 (NLRP3) inflammasome activation and the subsequent pyroptosis contr...

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Gepubliceerd in:Front Pharmacol
Hoofdauteurs: Mai, Weijian, Xu, Yangzhi, Xu, Jiahui, Zhao, Dan, Ye, Liangying, Yu, Ganxiang, Wang, Zhilei, Lu, Qianting, Lin, Jiaen, Yang, Tao, Gu, Chengxin, Liu, Shiming, Zhong, Yun, Yang, Hui
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2020
Onderwerpen:
Pharmacology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063468/
https://ncbi.nlm.nih.gov/pubmed/32194416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00185
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