Class C CpG Oligodeoxynucleotide Immunomodulatory Response in Aged Squirrel Monkey (Saimiri Boliviensis Boliviensis)

One means of stimulating the mammalian innate immune system is via Toll-like receptor 9 (TLR9) being exposed to unmethylated cytosine-phosphate-guanine (CpG) DNA, also known as pathogen-associated molecular patterns (PAMPs) of microbial origin. Synthetic CpG oligodeoxynucleotides (ODNs) with defined...

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Bibliographic Details
Published in:Front Aging Neurosci
Main Authors: Nehete, Pramod N., Williams, Lawrence E., Chitta, Sriram, Nehete, Bharti P., Patel, Akash G., Ramani, Margish D., Wisniewski, Thomas, Scholtzova, Henrieta
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063459/
https://ncbi.nlm.nih.gov/pubmed/32194391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2020.00036
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