DNA methylation profiling implicates exposure to PCBs in the pathogenesis of B-cell chronic lymphocytic leukemia()

OBJECTIVES: To characterize the impact of PCB exposure on DNA methylation in peripheral blood leucocytes and to evaluate the corresponding changes in relation to possible health effects, with a focus on B-cell lymphoma. METHODS: We conducted an epigenome-wide association study on 611 adults free of...

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Detalhes bibliográficos
Publicado no:Environ Int
Main Authors: Georgiadis, Panagiotis, Gavriil, Marios, Rantakokko, Panu, Ladoukakis, Efthymios, Botsivali, Maria, Kelly, Rachel S., Bergdahl, Ingvar A., Kiviranta, Hannu, Vermeulen, Roel C.H., Spaeth, Florentin, Hebbels, Dennie G.A.J., Kleinjans, Jos C.S., de Kok, Theo M.C.M., Palli, Domenico, Vineis, Paolo, Kyrtopoulos, Soterios A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063446/
https://ncbi.nlm.nih.gov/pubmed/30776747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.envint.2019.01.068
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