Macrophage-derived myeloid differentiation protein 2 plays an essential role in ox-LDL-induced inflammation and atherosclerosis

BACKGROUND: Atherosclerosis is a chronic inflammatory disease. Although Toll-like receptor 4 (TLR4) has been involved in inflammatory atherosclerosis, the exact mechanisms by which oxidized-low-density lipoproteins (ox-LDL) activates TLR4 and elicits inflammatory genesis are not fully known. Myeloid...

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Publicat a:EBioMedicine
Autors principals: Chen, Taiwei, Huang, Weijian, Qian, Jinfu, Luo, Wu, Shan, Peiren, Cai, Yan, Lin, Ke, Wu, Gaojun, Liang, Guang
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Research paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063167/
https://ncbi.nlm.nih.gov/pubmed/32151799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102706
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