Regulatory Role of Hexokinase 2 in Modulating Head and Neck Tumorigenesis

To support great demand of cell growth, cancer cells preferentially obtain energy and biomacromolecules by glycolysis over mitochondrial oxidative phosphorylation (OxPhos). Among all glycolytic enzymes, hexokinase (HK), a rate-limiting enzyme at the first step of glycolysis to catalyze cellular gluc...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Li, Wan-Chun, Huang, Chien-Hsiang, Hsieh, Yi-Ta, Chen, Tsai-Ying, Cheng, Li-Hao, Chen, Chang-Yi, Liu, Chung-Ji, Chen, Hsin-Ming, Huang, Chien-Ling, Lo, Jeng-Fan, Chang, Kuo-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063098/
https://ncbi.nlm.nih.gov/pubmed/32195170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00176
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