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Deep Learning to Predict Protein Backbone Structure from High-Resolution Cryo-EM Density Maps

Cryo-electron microscopy (cryo-EM) has become a leading technology for determining protein structures. Recent advances in this field have allowed for atomic resolution. However, predicting the backbone trace of a protein has remained a challenge on all but the most pristine density maps (<2.5 Å r...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Si, Dong, Moritz, Spencer A., Pfab, Jonas, Hou, Jie, Cao, Renzhi, Wang, Liguo, Wu, Tianqi, Cheng, Jianlin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063051/
https://ncbi.nlm.nih.gov/pubmed/32152330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60598-y
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