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Mitochondria as target to inhibit proliferation and induce apoptosis of cancer cells: the effects of doxycycline and gemcitabine

Doxycycline has anti-tumour effects in a range of tumour systems. The aims of this study were to define the role mitochondria play in this process and examine the potential of doxycycline in combination with gemcitabine. We studied the adenocarcinoma cell line A549, its mitochondrial DNA-less deriva...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Dijk, Sas N., Protasoni, Margherita, Elpidorou, Marilena, Kroon, Albert M., Taanman, Jan-Willem
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063048/
https://ncbi.nlm.nih.gov/pubmed/32152409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61381-9
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