Targeting the Oncogenic TBX2 Transcription Factor With Chromomycins

The TBX2 transcription factor plays critical roles during embryonic development and it is overexpressed in several cancers, where it contributes to key oncogenic processes including the promotion of proliferation and bypass of senescence. Importantly, based on compelling biological evidences, TBX2 h...

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Vydáno v:Front Chem
Hlavní autoři: Sahm, Bianca Del B., Peres, Jade, Rezende-Teixeira, Paula, Santos, Evelyne A., Branco, Paola C., Bauermeister, Anelize, Kimani, Serah, Moreira, Eduarda A., Bisi-Alves, Renata, Bellis, Claire, Mlaza, Mihlali, Jimenez, Paula C., Lopes, Norberto P., Machado-Santelli, Glaucia M., Prince, Sharon, Costa-Lotufo, Leticia V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Chemistry
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062867/
https://ncbi.nlm.nih.gov/pubmed/32195221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2020.00110
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