Functional hypoxia drives neuroplasticity and neurogenesis via brain erythropoietin

Erythropoietin (EPO), named after its role in hematopoiesis, is also expressed in mammalian brain. In clinical settings, recombinant EPO treatment has revealed a remarkable improvement of cognition, but underlying mechanisms have remained obscure. Here, we show with a novel line of reporter mice tha...

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發表在:Nat Commun
Main Authors: Wakhloo, Debia, Scharkowski, Franziska, Curto, Yasmina, Javed Butt, Umer, Bansal, Vikas, Steixner-Kumar, Agnes A., Wüstefeld, Liane, Rajput, Ashish, Arinrad, Sahab, Zillmann, Matthias R., Seelbach, Anna, Hassouna, Imam, Schneider, Katharina, Qadir Ibrahim, Abdul, Werner, Hauke B., Martens, Henrik, Miskowiak, Kamilla, Wojcik, Sonja M., Bonn, Stefan, Nacher, Juan, Nave, Klaus-Armin, Ehrenreich, Hannelore
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062779/
https://ncbi.nlm.nih.gov/pubmed/32152318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15041-1
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