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A critical role of PRDM14 in human primordial germ cell fate revealed by inducible degrons
PRDM14 is a crucial regulator of mouse primordial germ cells (mPGCs), epigenetic reprogramming and pluripotency, but its role in the evolutionarily divergent regulatory network of human PGCs (hPGCs) remains unclear. Besides, a previous knockdown study indicated that PRDM14 might be dispensable for h...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7062732/ https://ncbi.nlm.nih.gov/pubmed/32152282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15042-0 |
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