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Candesartan neuroprotection in rat primary neurons negatively correlates with aging and senescence; a transcriptomic analysis
Preclinical experiments and clinical trials demonstrated that Angiotensin II AT1 receptor overactivity associates with aging and cellular senescence, and that AT1 receptor blockers (ARBs) protect from age-related brain disorders. In a primary neuronal culture submitted to glutamate excitotoxicity, G...
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| Pubblicato in: | Mol Neurobiol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7062590/ https://ncbi.nlm.nih.gov/pubmed/31811565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-019-01800-9 |
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