Microglial depletion disrupts normal functional development of adult-born neurons in the olfactory bulb

Microglia play key roles in regulating synapse development and refinement in the developing brain, but it is unknown whether they are similarly involved during adult neurogenesis. By transiently depleting microglia from the healthy adult mouse brain, we show that microglia are necessary for the norm...

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Bibliographic Details
Published in:eLife
Main Authors: Wallace, Jenelle, Lord, Julia, Dissing-Olesen, Lasse, Stevens, Beth, Murthy, Venkatesh N
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2020
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062469/
https://ncbi.nlm.nih.gov/pubmed/32150529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50531
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