A COPII subunit acts with an autophagy receptor to target endoplasmic reticulum for degradation

The COPII-cargo adaptor complex, Lst1-Sec23, selectively sorts proteins into vesicles that bud from the endoplasmic reticulum (ER) and traffic to the Golgi. Improperly folded proteins are prevented from exiting the ER and are degraded. ER-phagy is an autophagic degradation pathway that utilizes ER-r...

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Veröffentlicht in:Science
Hauptverfasser: Cui, Yixian, Parashar, Smriti, Zahoor, Muhammad, Needham, Patrick G., Mari, Muriel, Zhu, Ming, Chen, Shuliang, Ho, Hsuan-Chung, Reggiori, Fulvio, Farhan, Hesso, Brodsky, Jeffrey L., Ferro-Novick, Susan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062386/
https://ncbi.nlm.nih.gov/pubmed/31273116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aau9263
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