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From cells to tissue: How cell scale heterogeneity impacts glioblastoma growth and treatment response

Glioblastomas are aggressive primary brain tumors known for their inter- and intratumor heterogeneity. This disease is uniformly fatal, with intratumor heterogeneity the major reason for treatment failure and recurrence. Just like the nature vs nurture debate, heterogeneity can arise from intrinsic...

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Detalles Bibliográficos
Publicado en:PLoS Comput Biol
Main Authors: Gallaher, Jill A., Massey, Susan C., Hawkins-Daarud, Andrea, Noticewala, Sonal S., Rockne, Russell C., Johnston, Sandra K., Gonzalez-Cuyar, Luis, Juliano, Joseph, Gil, Orlando, Swanson, Kristin R., Canoll, Peter, Anderson, Alexander R. A.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062288/
https://ncbi.nlm.nih.gov/pubmed/32101537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007672
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