Cell-free IgG-aggregates in plasma of patients with chronic lymphocytic leukemia cause chronic activation of the classical complement pathway

Therapy regimens for Chronic lymphocytic leukemia (CLL) commonly include chemotherapy and immunotherapy, which act through complement-mediated-cytotoxicity (CDC) and other mechanisms. CDC depends on several factors, including the availability and activity of the complement classical pathway (CP). Re...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Michelis, Regina, Tadmor, Tamar, Aviv, Ariel, Stemer, Galia, Majdob, Rawan, Shvidel, Lev, Shehadeh, Mona, Barhoum, Masad, Braester, Andrei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062264/
https://ncbi.nlm.nih.gov/pubmed/32150580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0230033
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