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On the relations of phase separation and Hi-C maps to epigenetics

The relationship between compartmentalization of the genome and epigenetics is long and hoary. In 1928, Heitz defined heterochromatin as the largest differentiated chromatin compartment in eukaryotic nuclei. Müller's discovery of position-effect variegation in 1930 went on to show that heteroch...

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Publicat a:R Soc Open Sci
Autors principals: Singh, Prim B., Newman, Andrew G.
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062049/
https://ncbi.nlm.nih.gov/pubmed/32257349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.191976
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