Radiosynthesis and preliminary evaluation of (11)C-labeled 4-cyclopropyl-7-(3-methoxyphenoxy)-3,4-dihydro-2H-benzo[e] [1,2,4] thiadiazine 1,1-dioxide for PET imaging AMPA receptors

The α-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) belong to the family of ionotropic transmembrane receptors for glutamate (iGluRs) that are implicated in the pathology of neurological disorders and neurodegenerative diseases. Inspired by a recently developed positive allo...

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Publicado en:Tetrahedron Lett
Autores principales: Chen, Jiahui, Gan, Jiefeng, Sun, Jiyun, Chen, Zhen, Fu, Hualong, Rong, Jian, Deng, Xiaoyun, Shang, Jingjie, Gong, Jian, Shao, Tuo, Collier, Lee, Wang, Lu, Xu, Hao, Liang, Steven H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062035/
https://ncbi.nlm.nih.gov/pubmed/32153306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2020.151635
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