GD2 chimeric antigen receptor modified T cells in synergy with sub-toxic level of doxorubicin targeting osteosarcomas

Since the prognosis for children with high-risk osteosarcoma (OS) remains suboptimal despite intensive multi-modality therapies, there is a clear and urgent need for the development of targeted therapeutics against these refractory malignancies. Chimeric antigen receptor (CAR) modified T cells can m...

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Bibliografiske detaljer
Udgivet i:Am J Cancer Res
Main Authors: Chulanetra, Monrat, Morchang, Atthapan, Sayour, Elias, Eldjerou, Lamis, Milner, Rowan, Lagmay, Joanne, Cascio, Matt, Stover, Brian, Slayton, William, Chaicumpa, Wanpen, Yenchitsomanus, Pa-Thai, Chang, Lung-Ji
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2020
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061749/
https://ncbi.nlm.nih.gov/pubmed/32195035
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