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Jump-seq: Genome-Wide Capture and Amplification of 5-Hydroxymethylcytosine Sites
5-Hydroxymethylcytosine (5hmC) arises from the oxidation of 5-methylcytosine (5mC) by Fe(2+) and 2-oxoglutarate-dependent 10–11 translocation (TET) family proteins. Substantial levels of 5hmC accumulate in many mammalian tissues, especially in neurons and embryonic stem cells, suggesting a potential...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7061342/ https://ncbi.nlm.nih.gov/pubmed/31117646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b02512 |
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