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Increased protein and mRNA expression of corticotropin-releasing factor (CRF), decreased CRF receptors and CRF binding protein in specific postmortem brain areas of teenage suicide subjects

Overactivity of hypothalamic-pituitary-adrenal (HPA) axis function has been implicated in depression and suicidal behavior. This is based on the observation of an abnormal dexamethasone (DEX) and DEX-adrenocorticotropic hormone (ACTH) test in patients with depression and suicidal behavior. Recently,...

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Dades bibliogràfiques
Publicat a:Psychoneuroendocrinology
Autors principals: Pandey, Ghanshyam N., Rizavi, Hooriyah S., Bhaumik, Runa, Ren, Xinguo
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061258/
https://ncbi.nlm.nih.gov/pubmed/31005044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2019.04.015
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