Hyaluronan 35 kDa enhances epithelial barrier function and protects against the development of murine necrotizing enterocolitis

BACKGROUND: Disruption of tight junctions (TJ) predisposes to bacterial translocation, intestinal inflammation, and necrotizing enterocolitis (NEC). Previously studies showed that hyaluronan (HA), a glycosaminoglycan in human milk, maintains intestinal permeability, enhances intestinal immunity, and...

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Bibliografiske detaljer
Udgivet i:Pediatr Res
Main Authors: Gunasekaran, Aarthi, Eckert, Jeffrey, Burge, Kathryn, Zheng, Wei, Yu, Zhongxin, Kessler, Sean, de la Motte, Carol, Chaaban, Hala
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061074/
https://ncbi.nlm.nih.gov/pubmed/31499514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41390-019-0563-9
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