In vivo CRISPR screen identifies TgWIP as a Toxoplasma modulator of dendritic cell migration

Toxoplasma can reach distant organs, especially the brain, leading to a lifelong chronic phase. However, genes involved in related in vivo processes are currently unknown. Here, we use focused CRISPR libraries to identify Toxoplasma genes that affect in vivo fitness. We focus on TgWIP whose deletion...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Sangaré, Lamba Omar, Ólafsson, Einar B., Wang, Yifan, Yang, Ninghan, Julien, Lindsay, Camejo, Ana, Pesavento, Patricia, Sidik, Saima M., Lourido, Sebastian, Barragan, Antonio, Saeij, Jeroen P.J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060943/
https://ncbi.nlm.nih.gov/pubmed/31600500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2019.09.008
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