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Inhibition of glycine cleavage system by pyridoxine 5′-phosphate causes synthetic lethality in glyA yggS and serA yggS in Escherichia coli
The YggS/Ybl036c/PLPBP family includes conserved pyridoxal 5′-phosphate (PLP)-binding proteins that plays a critical role in the homeostasis of vitamin B(6) and amino acids. Disruption of members of this family causes pleiotropic effects in many organisms by unknown mechanisms. In Escherichia coli,...
Zapisane w:
| Wydane w: | Mol Microbiol |
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| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2019
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7060791/ https://ncbi.nlm.nih.gov/pubmed/31677193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.14415 |
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